Medical Pharmacology and Therapeutics
Medical Pharmacology and Therapeutics,
Edition 5
By Derek G. Waller, BSc, DM, MBBS, FRCP and Anthony Sampson

Publication Date: 04 Aug 2017

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Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.

Key Features

 The fifth edition has been extensively revised and updated throughout. Key features include:

  • Clear, disease-based approach.

  • Presentation of how drugs are used in clinical practice.

  • Succinct explanations of the major pathogenic mechanisms of each disease and consequent clinical signs and symptoms.

  • Comprehensive reviews of major drug classes relevant to each disease.

  • Structured approach to the principles of disease management – outlining core principles of drug choice and planning a therapeutic regimen for common diseases.

  • Quick-reference drug compendia illustrating key similarities and differences among all BNF-listed drugs in each class.

New Features

  •  Comes with free e-book on StudentConsult.

  • New sections on key and evolving topics, including prescribing safety and pharmacovigilance.

  • Updated figures to further clarify complex areas.

  • Over 800 revised multiple-choice and case-based questions for self-assessment. 
About the author
By Derek G. Waller, BSc, DM, MBBS, FRCP, Consultant Cardiovascular Physician, Southampton General Hospital; Senior Lecturer in Medicine and Clinical Pharmacology, University of Southampton, Southampton, UK and Anthony Sampson
Table of Contents

SECTION 1 General principles

1. Principles of pharmacology and mechanisms of drug action

2. Pharmacokinetics

3. Drug discovery, safety and efficacy

4. The nervous system, neurotransmission and the peripheral autonomic
nervous system

SECTION 2 The cardiovascular system

5. Ischaemic heart disease

6. Systemic and pulmonary hypertension

7. Heart failure

8. Cardiac arrhythmias

9. Cerebrovascular disease and dementia

10. Peripheral vascular disease

11. Haemostasis

SECTION 3 The respiratory system

12. Asthma and chronic obstructive pulmonary disease

13. Respiratory disorders: cough, respiratory stimulants, cystic
fibrosis and neonatal respiratory distress syndrome

SECTION 4 The renal system

14. Diuretics

15. Disorders of micturition

16. Erectile dysfunction

SECTION 5 The nervous system

17. General anaesthetics

18. Local anaesthetics

19. Opioid analgesics and the management of pain

20. Anxiolytics, sedatives and hypnotics

21. The major psychotic disorders: schizophrenia and mania

22. Depression, attention deficit hyperactivity disorder and narcolepsy

23. Epilepsy

24. Extrapyramidal movement disorders and spasticity

25. Other neurological disorders: multiple sclerosis, motor neuron disease
and Guillain–Barré syndrome

26. Migraine

SECTION 6 The musculoskeletal system

27. The neuromuscular junction and neuromuscular blockade

28. Myasthenia gravis

29. Non-steroidal anti-inflammatory drugs

30. Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis

31. Hyperuricaemia and gout

SECTION 7 The gastrointestinal system

32. Nausea and vomiting

33. Dyspepsia and peptic ulcer disease

34. Inflammatory bowel disease

35. Constipation, diarrhoea and irritable bowel syndrome

36. Liver disease

37. Obesity

SECTION 8 The immune system

38. The immune response and immunosuppressant drugs

39. Antihistamines and allergic disease

SECTION 9 The endocrine system and metabolism

40. Diabetes mellitus

41. The thyroid and control of metabolic rate

42. Calcium metabolism and metabolic bone disease

43. Pituitary and hypothalamic hormones

44. Corticosteroids (glucocorticoids and mineralocorticoids)

45. Female reproduction

46. Androgens and anabolic steroids

47. Anaemia and haematopoietic colony-stimulating factors

48. Lipid disorders

SECTION 10 The skin and eyes

49. Skin disorders

50. The eye

SECTION 11 Chemotherapy

51. Chemotherapy of infections

52. Chemotherapy of malignancy

SECTION 12 General features: toxicity and prescribing

53. Drug toxicity and overdose

54. Substance abuse and dependence

55. Prescribing, adherence and information about medicines

56. Drug therapy in special situations


Book Reviews

"Overall, the strengths of this text include its organisation and position of pharmacological information in a clinical context, its accessible language and engaging format ... A succinct yet broad scope of topics enhances the desirability of this text to those who design and deliver an integrated curriculum, and also to the student who wishes to learn what is typically regarded as a difficult, but most essential topic, in a relevant and approachable way."

2018 BMA Awards: Highly Commended, Medicine  

From reviews of the previous edition:

‘As a medical student, I had previously studied Pharmacology … with a book that made me hate Pharmacology! Most people who, like I did, have read that book, will agree that another Pharmacology textbook would be better to use later to review some subjects (it is amazing how Pharmacology vanishes so swiftly from our heads!). I quickly found this one. A quick glance at the table of contents and I immediately understood I wanted to purchase it. It did not take long for me to notice this was the best choice I could have made. Waller's Medical Pharmacology and Therapeutics offers a broad covering, with straight-to-the-point explanations. It never goes into unnecessary detail, although sometimes a little more detail would be desirable (for example, more information on drug interactions).Summing it up, in comparison, Waller's has a broader coverage, less detail, clearer writing and is a better source for a quick review. Remember that I hated Pharmacology before? Well, I ended up loving it - such is the difference a good textbook makes.’

Book details
ISBN: 9780702071676
Page Count: 734
Illustrations: Approx. 158 illustrations (158 in full color)
Retail Price: £49.99