Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.
The fifth edition has been extensively revised and updated throughout. Key features include:
- Clear, disease-based approach.
- Presentation of how drugs are used in clinical practice.
- Succinct explanations of the major pathogenic mechanisms of each disease and consequent clinical signs and symptoms.
- Comprehensive reviews of major drug classes relevant to each disease.
- Structured approach to the principles of disease management – outlining core principles of drug choice and planning a therapeutic regimen for common diseases.
- Quick-reference drug compendia illustrating key similarities and differences among all BNF-listed drugs in each class.
- Comes with free e-book on StudentConsult.
- New sections on key and evolving topics, including prescribing safety and pharmacovigilance.
- Updated figures to further clarify complex areas.
- Over 800 revised multiple-choice and case-based questions for self-assessment.
SECTION 1 General principles
1. Principles of pharmacology and mechanisms of drug action
3. Drug discovery, safety and efficacy
4. The nervous system, neurotransmission and the peripheral autonomic
SECTION 2 The cardiovascular system
5. Ischaemic heart disease
6. Systemic and pulmonary hypertension
7. Heart failure
8. Cardiac arrhythmias
9. Cerebrovascular disease and dementia
10. Peripheral vascular disease
SECTION 3 The respiratory system
12. Asthma and chronic obstructive pulmonary disease
13. Respiratory disorders: cough, respiratory stimulants, cystic
fibrosis and neonatal respiratory distress syndrome
SECTION 4 The renal system
15. Disorders of micturition
16. Erectile dysfunction
SECTION 5 The nervous system
17. General anaesthetics
18. Local anaesthetics
19. Opioid analgesics and the management of pain
20. Anxiolytics, sedatives and hypnotics
21. The major psychotic disorders: schizophrenia and mania
22. Depression, attention deficit hyperactivity disorder and narcolepsy
24. Extrapyramidal movement disorders and spasticity
25. Other neurological disorders: multiple sclerosis, motor neuron disease
and Guillain–Barré syndrome
SECTION 6 The musculoskeletal system
27. The neuromuscular junction and neuromuscular blockade
28. Myasthenia gravis
29. Non-steroidal anti-inflammatory drugs
30. Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis
31. Hyperuricaemia and gout
SECTION 7 The gastrointestinal system
32. Nausea and vomiting
33. Dyspepsia and peptic ulcer disease
34. Inflammatory bowel disease
35. Constipation, diarrhoea and irritable bowel syndrome
36. Liver disease
SECTION 8 The immune system
38. The immune response and immunosuppressant drugs
39. Antihistamines and allergic disease
SECTION 9 The endocrine system and metabolism
40. Diabetes mellitus
41. The thyroid and control of metabolic rate
42. Calcium metabolism and metabolic bone disease
43. Pituitary and hypothalamic hormones
44. Corticosteroids (glucocorticoids and mineralocorticoids)
45. Female reproduction
46. Androgens and anabolic steroids
47. Anaemia and haematopoietic colony-stimulating factors
48. Lipid disorders
SECTION 10 The skin and eyes
49. Skin disorders
50. The eye
SECTION 11 Chemotherapy
51. Chemotherapy of infections
52. Chemotherapy of malignancy
SECTION 12 General features: toxicity and prescribing
53. Drug toxicity and overdose
54. Substance abuse and dependence
55. Prescribing, adherence and information about medicines
56. Drug therapy in special situations
"Overall, the strengths of this text include its organisation and position of pharmacological information in a clinical context, its accessible language and engaging format ... A succinct yet broad scope of topics enhances the desirability of this text to those who design and deliver an integrated curriculum, and also to the student who wishes to learn what is typically regarded as a difficult, but most essential topic, in a relevant and approachable way."
2018 BMA Awards: Highly Commended, Medicine
From reviews of the previous edition:
‘As a medical student, I had previously studied Pharmacology … with a book that made me hate Pharmacology! Most people who, like I did, have read that book, will agree that another Pharmacology textbook would be better to use later to review some subjects (it is amazing how Pharmacology vanishes so swiftly from our heads!). I quickly found this one. A quick glance at the table of contents and I immediately understood I wanted to purchase it. It did not take long for me to notice this was the best choice I could have made. Waller's Medical Pharmacology and Therapeutics offers a broad covering, with straight-to-the-point explanations. It never goes into unnecessary detail, although sometimes a little more detail would be desirable (for example, more information on drug interactions).Summing it up, in comparison, Waller's has a broader coverage, less detail, clearer writing and is a better source for a quick review. Remember that I hated Pharmacology before? Well, I ended up loving it - such is the difference a good textbook makes.’