Genomic and Precision Medicine,
Edition 3 Foundations, Translation, and Implementation
Edited by Geoffrey S. Ginsburg and Huntington F Willard

Publication Date: 09 Dec 2016

Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care.

The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.

Key Features

  • Provides a comprehensive volume on the translation and implementation of biology into health care provision
  • Presents succinct commentary and key learning points that will assist readers with their local needs for translation and implementation
  • Includes an up-to-date overview on major ‘translational events’ in genomic and personalized medicine, along with lessons learned
About the author
Edited by Geoffrey S. Ginsburg, Chief Medical and Scientific Officer, All of Us Research Program, National Institutes of Health, Bethesda, Maryland, USA and Huntington F Willard, Chief Scientific Officer, Genome Medical, Inc., South San Francisco, CA, USA
Table of Contents
1. Application of Human Genome Information to Clinical Practice
1a. Genome sequencing: new technologies, approaches, applications
1b. Clinical applications of whole-genome chromosomal microarray analysis
1c. Transcriptomics in the age of ultra high-throughput sequencing
1d. Quantitative Proteomics in Genomic Medicine
2. Translating genome information into clinical practice and human health
3. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
3a. Biospecimen Banking linked to phenotype data
3b. Electronic Health Records
3c. Data Sharing and Privacy
4. Designing Genome-Based Clinical Studies
5. Developing the Evidence to Support Clinical Use Genomic Biomarkers as Diagnostics
5a. Strategies in the Adoption of Genome-Based Diagnostics
5b. Companion Diagnostics
6. Health Risk Assessment and Family History
7. Clinical Decision Support
8. Implementation Science and Integration into Healthcare Systems
9. Pharmacogenetics and Pharmacogenomics
10. Drug Repurposing and Repositioning
11. Point of Care Devices
12. Overview of Policy, Ethical and Social Considerations
13. Educational Issues and Strategies for Genomic Medicine: 
13a. For Professionals
13b. For The Public
14. Regulation of Genomic Technologies
15. Economic Value of Genomic Medicine
16. Reimbursement
17. Impact of Patents on Genomic Medicine
Book details
ISBN: 9780128006818
Page Count: 398
Retail Price : £89.99
  • Ginsburg and Willard, Genomic and Personalized Medicine, 2008, 9780123694201, 1250pp, $465.00
  • Ginsburg and Willard, Essentials of Genomic and Personalized Medicine, Sep 2009, 9780123749345, 800pp, $144.00
  • Ginsburg and Willard, Genomic and Personalized Medicine 2e, Nov 2012, 9780123822277, 1,350pp, $450.00
Medical students, life sciences and engineering graduate students, advanced undergraduate students, residents and fellows working with any aspect of genomic research in the life sciences and/or medicine, educators, and translational scientists. This volume will also be of interest to translational researchers, implementation scientists, outcomes researchers, policy analysts and policy makers
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