Neurodevelopmental Disorders,
Edition 1 Comprehensive Developmental Neuroscience
Edited by Bin Chen, Kenneth Y. Kwan, John Rubenstein and Pasko Rakic

Publication Date: 27 May 2020

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms.

Key Features

  • Features leading experts in various subfields as section editors and article authors
  • Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship
  • Covers disorders of the nervous system that arise through defects in neural development
About the author
Edited by Bin Chen, Professor of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, USA; Kenneth Y. Kwan, Assistant Professor of Human Genetics and Research Assistant Professor, Molecular and Behavioral Neuroscience Institute, University of Michigan, USA; John Rubenstein, Professor, Department of Psychiatry, University of California, San Francisco, USA and Pasko Rakic, Department of Neuroscience, Yale School of Medicine, USA
Table of Contents


1. Neurocutaneous Syndromes: Neurofibromatosis and Tuberous Sclerosis

Mustafa Sahin

2. Azetidine-2-Carboxylic Acid and Other Nonprotein Amino Acids in the Pathogenesis of Neurodevelopmental Disorders

Edward Rubenstein

3. Autisms

Antonio M. Persico

4. Developmental basis of ZIKA virus induced neuropathology

Hongjun Song and Guo-li Ming

5. iPSC Models of Human Neurodevelopmental Disorders

Flora M. Vaccarino

6. Cornelia de Lange Syndrome: Insights into Neural Development from Clinical Studies and Animal Models

Anne Leighton Calof, Rosaysela Santos, Laura Groves, Chris Oliver and Arthur D. Lander

7. Fetal Alcohol Spectrum Disorder

Sandra Mooney

8. Neural Tube Defects

Lee Niswander

9. Developmental disabilities, autism and schizophrenia at a single locus: complex gene regulation and genomic instability of 15q11-q13 cause a range of neurodevelopmental disorders

Lawrence T. Reiter

10. Lissencephalies

Elliott Sherr and Bethany Johnson-Kerner

11. Rett Syndrome

Jeffrey Lorenz Neul

12. Focal Cortical Dysplasias

Christopher A. Walsh and Alissa M. D’Gama

13. White Matter Disorders

Benjamin Lawrence Lynner Clayton, Paul Tesar, Kevin Cameron Allan, Zachary Scott Nevin and Matthew Sean Elitt

14. Language Impairments

R. Holly Fitch

15. Fragile X Syndrome

Randi Hagerman

16. Microcephalies

Youngshin Lim and Jeffrey Alan Golden

Book details
ISBN: 9780128144091
Page Count: 426
Retail Price : £118.00
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  • Sweatt/Meaney/Nestler/Akbarian, Epigenetic Regulation in the Nervous System: Basic Mechanisms and Clinical Impact 1e, Feb. 2013, 9780123914941,
  • Zigmond, Neurobiology of Brain Disorders 1e, Dec. 2014, 9780123982704,
Neuroscience, developmental biology researchers, including stem cells, aging and diseases. Translational neuroscience researchers
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