Purchase textbook

Opioids,

Edition 1

Editors: By George F. Koob, Michael A. Arends, BS, Mandy L McCracken and Michel Le Moal

Publication Date: 01 Jun 2023

0 Reviews

Conformance

PDF/UA-1
The publication was certified on 20250728
For queries regarding accessibility information, contact [email protected]

Ways Of Reading

This e-publication is accessible to the full extent that the file format and types of content allow, on a specific reading device, by default, without necessarily including any additions such as textual descriptions of images or enhanced navigation.

Navigation

The contents of the PDF have been tagged to permit access by assistive technologies as per PDF-UA-1 standard.
Page breaks included from the original print source

Additional Accessibility Information

The language of the text has been specified (e.g., via the HTML or XML lang attribute) to optimise text-to-speech (and other alternative renderings), both at the whole document level and, where appropriate, for individual words, phrases or passages in a different language.

Note

This product relies on 3rd party tooling which may impact the accessibility features visible in inspection copies. All accessibility features mentioned would be present in the purchased version of the title.

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.

Key Features

Highlights recent advances in opioid addiction
Includes Neurocircuitry, Cellular and Molecular neurobiological mechanisms of opioid addiction
Defines opioid abuse and addiction potential, including biological tolerance

About the author

By George F. Koob, Director, National Institute on Alcohol Abuse and Alcoholism and National, Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA; Michael A. Arends, BS, Senior Research Assistant, The Scripps Research Institute, La Jolla, CA, USA; Mandy L McCracken, Waggoner Center for Alcohol and Addiction Research, The University of Texas, Austin, TX, USA and Michel Le Moal, Professor Emeritus, University of Bordeaux and Neurocentre Magendie, Inserm, Bordeaux, France

1. Definitions
2. History of opioid use
3. Mechanism of action: endogenous opioid system
4. Physiological effects
5. Behavioral effects
6. Pharmacokinetics
7. Behavioral mechanism of action
8. Medical use, abuse, and addiction
9. Neurobiological effects
10. Summary

ISBN: 9780128169889

Page Count: 424

Retail Price :

9780123736253; 9780123869371; 9780123983367; 9780124186798

Primary: Researchers and graduate students in neuroscience, neurology, psychiatry, and addiction medicine