Sperling Pediatric Endocrinology,
Edition 5Editors: By Mark A. Sperling, MD
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An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you’re preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient.
Key Features
- Delivers trusted guidance in every area of the field: including Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests
- Features new topics such as transgender issues in children and adolescents and endocrinology of pregnancy, the fetus and the placenta
- Offers expert coverage of hot topics such as disorders of sexual development, molecular basis of endocrine disorders, hypoglycemia in newborns and infants; neonatal and other monogenic forms of diabetes; Type I and Type II diabetes and their treatment with new insulins together with the progress in an artificial pancreas and new medications for T2DM in adolescents; the obesity epidemic and role of bariatric surgery; and advances toward personalized medicine
- Includes easy-to-follow algorithms and numerous quick-reference tables and boxes in every clinical chapter, plus interactive questions online for self-assessment
- Offers state-of-the-art information and fresh perspectives from new and award-winning authors in such areas as disorders of growth, multiple endocrine tumors, and puberty and its disorders in girls and boys
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
About the author
By Mark A. Sperling, MD, Professor and Chair Emeritus, Department of Pediatrics, University of Pittsburgh School of Medicine and Division of Endocrinology, Metabolism, and Diabetes Mellitus, Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
SECTION I Principles and Methods of Pediatric Endocrinology, 1
1. Overview and Principles of Pediatric Endocrinology, 1
Mark A. Sperling
2. Molecular Endocrinology, Endocrine Genetics, and Precision Medicine, 9
Ram K. Menon, Massimo Trucco, Joseph A. Majzoub, Constantine A. Stratakis
3. Receptor Transduction Pathways Mediating Hormone Action, 30
Bassil Kublaoui, Michael A. Levine
4. Endocrinology Laboratory Testing, 86
Jon Nakamoto
SECTION II Endocrine Disorders in the Neonate, 106
5. Fetal-Maternal Endocrinology and Parturition, 106
Sam Mesiano, Helen N. Jones, Heide Aungst, Tani Malhotra, Louis J. Muglia
6. Ambiguous Genitalia, 123
Selma Feldman Witchel, Peter A. Lee
7. Hypoglycemia in the Newborn and Infant, 175
Diva D. De Leon, Paul Thornton, Charles A. Stanley, Mark A. Sperling
8. Disorders of the Thyroid in the Newborn and Infant, 202
Johnny Deladoey, Julia Elisabeth von Oettingen, Guy Van Vliet
9. Disorders of Mineral Metabolism: Normal Homeostasis, 220
Allen W. Root
10. Monogenic Diabetes Mellitus: Neonatal Diabetes and Maturity-Onset Diabetes of the Young, 279
Siri Atma W. Greeley*, Mary K. McCauley*, Louis H. Philipson, Mark A. Sperling
*Authors contributed equally to this chapter
SECTION III Childhood and Adolescent Endocrinology, 299
11. Disorders of Childhood Growth, 299
Alexander A.L. Jorge, Adda Grimberg, Mehul T. Dattani, Jeffrey Baron
12. Disorders of the Posterior Pituitary, 357
Abhinash Srivatsa, Joseph A. Majzoub
13. Thyroid Disorders in Children and Adolescents, 395
Scott Rivkees, Andrew J. Bauer
14. The Adrenal Cortex and Its Disorders, 425
Walter L. Miller, Christa E. Flück, David T. Breault, Brian J. Feldman
15. Pheochromocytoma/Paraganglioma, Medullary Thyroid Carcinoma, and Hereditary Endocrine Neoplasia Syndromes, 491
Steven G. Waguespack, Lauren Fishbein
16. Puberty in the Female and Its Disorders, 528
Robert L. Rosenfield, David W. Cooke, Sally Radovick
17. Turner Syndrome, 627
Philippe Backeljauw, Steven D. Chernausek, Claus Højbjerg Gravholt, Paul Kruszka
18. Puberty and Its Disorders in the Male, 661
Mark R. Palmert, Yee-Ming Chan, Leo Dunkel
19. Care of Transgender/Gender Nonconforming Youth, 695
Stephen M. Rosenthal, Amy B. Wisniewski
20. Disorders of Mineral Metabolism II. Abnormalities of Mineral Homeostasis in the Newborn, Infant, Child, and Adolescent, 705
Allen W. Root, Michael A. Levine
21. Diabetes Mellitus, 814
Mark A. Sperling, Joseph I. Wolfsdorf, Ram K. Menon, William V. Tamborlane, David Maahs, Tadej Battelino, Moshe Phillip
22. Autoimmune Polyglandular Syndromes, 884
Bimota Nambam, Michael J. Haller, William E. Winter, Desmond Schatz
23. Hypoglycemia in the Toddler and Child, 904
Joseph I. Wolfsdorf, Charles A. Stanley
24. Obesity, Metabolic Syndrome and Disorders of Energy Balance, 939
Joan C. Han, Ram Weiss
25. Lipid Disorders in Children and Adolescents, 1004
Stephen R. Daniels, Sarah C. Couch
