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Manual of Hematopoietic Cell Transplantation and Cellular Therapies,

Edition 1

Editors: Edited by Qaiser Bashir, MD, Elizabeth J. Shpall, MD and Richard E. Champlin, MD

Publication Date: 06 Mar 2023

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**Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Transplantation Surgery**

Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies.

Key Features

Addresses hematologic conditions including leukemia, lymphoma, and myeloma
Offers guidance on hematopoietic cell transplantation for solid tumors
Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications
Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT
Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference
Offers team-based, clinically-focused coverage from world-renowned leaders in the field
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

About the author

Edited by Qaiser Bashir, MD, Associate Professor of Medicine, Department of Stem Cell Transplantation & Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Elizabeth J. Shpall, MD, Professor and Chair, at interim, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer MedicineDirector, Cell Therapy Laboratory, Director, Cord Blood Bank, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA and Richard E. Champlin, MD, Professor, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

PART I: Introduction and Biological Aspects
1. Hematopoietic Transplantation: Past, Present, and Future
2. Role of the Human Leukocyte Antigen System in Hematopoietic Stem Cell Transplantation

PART II: Methodology
3. Hematopoietic Cell Collection
4. Bayesian Statistical Methods in Stem Cell Transplantation and Cellular Therapy

PART III: General Clinical Aspects
5. Patient and Donor Assessments in Preparation for Transplant
6. Transfusion Support During Hematopoietic Cell Transplantation
7. Haploidentical Hematopoietic Cell Transplantation
8. Umbilical Cord Blood Transplantation
9. Process and General Management of Patients Undergoing Chimeric Antigen Receptor Therapies

PART IV: Pharmacology and Radiation Therapy
10. Preparative Regimens Used in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapies
11. Pharmacology of Drugs Used in Hematopoietic Cell Transplant and Chimeric Antigen Receptor Therapies
12. Radiobiologic Principles and the Role of Radiotherapy in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy

PART V: Disease-Specific Indications and Results
13. Hematopoietic Cell Transplantation in Adult With Acute Myeloid Leukemia
14. Chimeric Antigen Receptor Therapy in Acute Myeloid Leukemia
15. Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia
16. Chimeric Antigen Receptor T-Cell Therapy in Acute Lymphoblastic Leukemia
17. Hematopoietic Cell Transplantation and Other Cellular Therapies for Chronic Lymphocytic Leukemia
18. Allogeneic Hematopoietic Cell Transplantation in Myelodysplastic Syndrome Patients
19. Allogeneic Cell Transplantation for Myeloproliferative Neoplasms
20. Hematopoietic Cell Transplantation in Aplastic Anemia
21. Hematopoietic Cell Transplantation in Multiple Myeloma
22. Chimeric Antigen Receptor Therapy in Multiple Myeloma
23. Hematopoietic Cell Transplantation in Light Chain Amyloidosis
24. Hematopoietic Cell Transplantation for Non-Hodgkin Lymphoma
25. Hematopoietic Cell Transplantation for Hodgkin Lymphoma
26. Chimeric Antigen Receptor Therapy in Lymphoma
27. Hematopoietic Cell Transplantation in Rare Hematologic Malignancies
28. Hematopoietic Cell Transplantation for Germ-Cell Tumors and Other Adult Solid Tumors
29. Natural Killer Cells: A Promising Cellular Therapy Platform to Conquer Cancer

PART VI: Prevention and Management of Complications
30. Infection Control, Prophylaxis, and Vaccinations in Hematopoietic Cell Transplantation Recipients
31. Management of Infections in Stem Cell Transplant Recipients
32. Graft Failure After Hematopoietic Cell Transplantation
33. Graft-Versus-Host Disease
34. Miscellaneous Complications of Hematopoietic Cellular Transplantation
35. Cytokine Release Syndrome Following CD19 Directed Chimeric Antigen Receptor T-Cell Therapy
36. Neurologic Complications of Chimeric Antigen Receptor Therapy
37. Miscellaneous Complications of Chimeric Antigen Receptor T-Cell Therapy
38. Symptom Management and Palliative Care in Hematologic Malignancies
39. Survivorship

Manual of Hematopoietic Cell Transplantation and Cellular Therapies,

Editors: Edited by Qaiser Bashir, MD, Elizabeth J. Shpall, MD and Richard E. Champlin, MD

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