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Aminoff's Diagnosis of Neuromuscular Disorders,

Edition 4

Editors: By Michael J. Aminoff, MD, DSc, FRCP, Jeffrey W. Ralph, MD and Francis Walker, MD

Publication Date: 01 Apr 2024

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Selected for 2025 Doody’s Core Titles® in Neurology

Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?”

Key Features

Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process
Reviews neuromuscular physiology and the pathology of major diseases
Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states
Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves
Features video clips of waveforms and of ultrasound images to illustrate key concepts
An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

About the author

By Michael J. Aminoff, MD, DSc, FRCP, Distinguished Professor Emeritus in Neurology; University of California San Francisco, USA; Jeffrey W. Ralph, MD, Clinical Professor; Director, Neuromuscular Medicine Fellowship Program; University of California San Francisco, USA; Francis Walker, MD, Emeritus Professor of Neurology and Wake Forest University School of Medicine, USA

PART I Introduction
1. Diagnosis of Neuromuscular Disorders
2. Biopsies and Neuromuscular Disease
3. Neuromuscular Imaging, 38
4. Genetic Evaluation of Neuromuscular Disorders

PART II Basic Aspects
5. Aspects of Nerve and Muscle Physiology
6. Properties and Functional Organization of Motor Units
7. Electrodiagnostic Apparatus
8. General Aspects of Needle Electromyography
9. Clinical Aspects of Needle Electromyography
10. Nerve Conduction Studies: Basic Principles and Pathologic Correlations
11. Quantitative and Related Techniques of Electromyography and Electroneurography
12. Other Neurophysiologic Techniques for the Evaluation of Neuromuscular Disorders
13. Evaluation of the Autonomic Nervous System

PART III Generalized Neuromuscular Disorders
14. Myopathic Disorders and Myalgia
15. Muscle Channelopathies
16. Motor Neuron Disorders
17. Muscle Fiber and Motor Unit Hyperactivity States
18. Polyneuropathy and Mononeuropathy Multiplex
19. Root and Plexus Lesions
20. Neuromuscular Transmission and Its Disorders

PART IV Focal Neuropathies
21. Traumatic Neuropathy and Surgical Interventions Focal Neuropathies in the Upper Limbs
22. Median Neuropathies
23. Ulnar Neuropathies
24. Radial Neuropathies
25. Disturbances of Other Nerves in the Upper Extremities Focal Neuropathies in the Lower Limbs
26. Fibular (Peroneal) Neuropathies
27. Tibial and Sural Neuropathies
28. Sciatic Neuropathies
29. Disturbances of Other Nerves in the Lower Extremities Cranial Nerves
30. Facial Neuropathies
31. Disturbances of Other Cranial Nerves and the Phrenic Nerve

PART V Central Nervous System
32. Electrophysiologic Evaluation of Selected Aspects of the Central Nervous System

Appendix
1: Glossary of Terms in Neuromuscular and Electrodiagnostic Medicine and Ultrasound
2: Nerve Reference Values for Ultrasonography
3: Videos

Book Reviews

"This book is a clinical guide to approaching neuromuscular disorders through pathophysiology, diagnosis, and management. The book is mostly in text format; however, it has many pictures, tables, and graphs to easily find highlights. The accompanying website has the complete eBook as well as videos that complement examples of pathology. The previous edition was published in 1998." - ©Doody’s Review Service, 2024, Patricia J Graese, MD (Thomas Jefferson University), Doody’s Score: 100 - 5 Stars!

ISBN: 9780323871068

Page Count: 720

Retail Price :

clinical neurologists and physiatrists, neuromuscular clinicians, and clinical neurophysiologists and electromyographers. It will also be an important reference source for trainees and those preparing for board certification in neurology, physiatry (physical medicine and rehabilitation), neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine