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The Sepsis Codex,

Edition 1

Editors: Edited by Marcio Borges, MD, Jorge Hidalgo, MD, MACP, MCCM, FCCP and Javier Perez-Fernandez, MD

Publication Date: 02 Dec 2022

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Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A “one size fits all¿ approach is not sufficient to meet individual patients’ needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area.

Key Features

Covers pathophysiology, early detection, biomarkers and diagnosis, therapies, controversies, future research, the use of AI, professional organizations and public health in sepsis.
Includes chapters on sepsis in special populations such as in pregnant women, transplanted patients, and children.
Consolidates today's available information on this timely topic into a single, convenient resource.

About the author

Edited by Marcio Borges, MD, Associate Professor of Infectious Disease Balearic Islands University; Coordinator, Multidisciplinary Sepsis Unit, Critical Care Medicine, Son Llatzer University Hospital, Palma de Mallorca, Spain; Jorge Hidalgo, MD, MACP, MCCM, FCCP, Professor and Head, Division of Critical care, Karl Heusner Memorial Hospital, Belize, Central America, Belize and Javier Perez-Fernandez, MD, Medical Director, Critical Care Services Baptist Hospital of Miami, Florida, USA

PART I INTRODUCTION
1 Sepsis: Past, Present, and Futured Lessons Learned from COVID-19
2 Sepsis Definitions: A Historical Perspective
3 The Epidemiology of Sepsis
PART II BASIC CONCEPTS
4 Pathophysiology of Sepsis
5 Sepsis and Microcirculation
6 Genetics and Sepsis
PART III DIAGNOSIS AND MONITORING
7 Screening and early detection of sepsis
8 Diagnosis and Monitoring of Sepsis
9 Sepsis: Molecular Diagnostics and Biomarkers
10 Hemodynamic Monitoring: Current Practice and New Perspectives
11 Point of Care Ultrasound in the Management of Sepsis
12 New Approaches and Understanding of Sepsis
13 Sepsis Quality Indicators in the Emergency Department
PART IV TREATMENT
14 Sepsis Treatment: Fluids
15 Vasopressor Therapy in Septic Shock
16 Mechanical Ventilation in Sepsis
17 Extracorporeal Membrane Oxygenation for the Support of Patients with Refractory Septic Shock
18 Antimicrobials in the Management of Sepsis
19 Kidney Support in Sepsis
20 Hematological Support in Sepsis
21 Specific Treatment of Focus Control in Sepsis
22 Sepsis Adjunctive Therapies
23 Glycemic Control and Stress Ulcer Prophylaxis
24 Nutrition in Sepsis
PART V SPECIAL SETTINGS
25 Fever in Intensive Care Units
26 SepsisdIn the Era of Antimicrobial Resistance
27 Factors Underlying Racial and Gender Disparities in Sepsis Management
28 Sepsis in Special Populations
29 Comprehensive Management of Sepsis in Pediatrics
30 Maternal Sepsis
PART VI SPECIAL CONSIDERATIONS
31 Role of Preventive Measures in Sepsis
32 Value of the Protocolization and Sepsis Performance Improvement Program in Early Identification
33 Long-Term Sequelae of Sepsis
PART VII FUTURE OUTLOOK
34 New Diagnostic and Therapeutic Perspectives
35 Artificial Intelligence in Sepsis
INDEX

The Sepsis Codex,

Editors: Edited by Marcio Borges, MD, Jorge Hidalgo, MD, MACP, MCCM, FCCP and Javier Perez-Fernandez, MD

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About the author