Essentials of Medical Biochemistry, Third Edition offers a condensed, yet detailed overview of clinical biochemistry, spanning fundamentals and relevant physiologic and pathophysiologic concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis.
Users will find fundamental concepts aiding students and professionals in biochemistry, medicine, and other healthcare disciplines. The text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists.
This Third Edition has been fully updated to address evolving techniques in the biological sciences, including genomics, metabolomics, transcriptomics, epigenomics, proteomics, and gene therapy, among other methods. In addition, each chapter has been fully revised for current science and now features learning objectives and chapter summaries, supplemental reading, and 5 clinical case based multiple choice questions. New clinical cases have been added throughout.
Key Features
- Integrates the biochemical principles with physiological, pharmacological, and pathological aspects of human diseases
- Each chapter features learning objectives, summaries, required and supplemental reading lists, clinical cases, and multiple-choice questions
- Presents essential biochemical concepts within the context of their biological functions Offers instructional overview figures, flowcharts, tables and multi-colored illustrations
- Provides an online ancillary package with PowerPoint images and an additional 500 study questions to aid in comprehension and USMLE exam preparation
1. The Human Organism: Organ Systems, Cells, Organelles, and Our Microbiota
2. Water, Acids, Bases, and Buffers
3. Amino Acids
4. Three-Dimensional Structure of Proteins and Disorders of Protein Misfolding
5. Energetics of Biological Systems, Enzymes and Enzyme Regulation
6. Clinical Enzymology and Biomarkers of Tissue Injury
7. Simple Carbohydrates
8. Heteropolysaccharides: Glycoconjugates, Glycoproteins, and Glycolipids
9. Connective Tissue: Fibrous and Nonfibrous Proteins and Proteoglycans
10. Gastrointestinal Digestion and Absorption
11. Carbohydrate Metabolism I: Glycolysis and the Tricarboxylic Acid Cycle
12. Electron Transport Chain, Oxidative Phosphorylation, and Other Oxygen-Consuming Systems
13. Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways
14. Protein and Amino Acid Metabolism
15. Lipids I: Fatty Acids and Eicosanoids
16. Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
17. Lipids III: Plasma Lipoproteins
18. Contractile Systems
19. Perturbations of Energy Metabolism: Obesity and Diabetes Mellitus
20. Structure and Properties of DNA
21. DNA Replication, Repair, and Mutagenesis
22. RNA and Protein Synthesis
23. Regulation of Gene Expression
24. Nucleotide Metabolism
25. Hemoglobin and Metabolism of Iron & Heme
26. Endocrine Metabolism I: Introduction and Signal Transduction
27. Endocrine Metabolism II: Hypothalamus and Pituitary
28. Endocrine Metabolism III: Adrenal Glands
29. Endocrine Metabolism IV: Thyroid Gland
30. Endocrine Metabolism V: Reproductive System
31. Immunology
32. Biochemistry of Hemostasis
33. Mineral Metabolism
34. Vitamin Metabolism
35. Drug Metabolism
A very useful text, well-written and illustrated and up to date.
Me parece un libro muy completo y me gusta la exposición de los casos clínicos. Suelen ser de mucha utilidad para los alumnos pues exponen las aplicaciones de la bioquímica
A simplified, easy-to-follow text with clear illustrations and strong medical applications and links.