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Miller's Anesthesia, 2-Volume Set,

Edition 10

Editors: Edited by Michael A. Gropper, MD, PhD, Lars I. Eriksson, MD, Lee A. Fleisher, MD, Neal H. Cohen, MD, MPH, MS, Kate Leslie, MD and Oluwaseun Johnson-Akeju, MD

Publication Date: 03 Sep 2024

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Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Anesthesiology & Pain Medicine

Offering up-to-date coverage of everything from historical and international perspectives to basic science and today’s clinical practice, Miller's Anesthesia, 10th Edition, remains the #1 reference and trusted learning resource for practitioners and trainees in this complex field. Dr. Michael Gropper leads a team of expert editors and contributing authors who provide current information on the technical, scientific, and clinical issues you face each day—whether you’re managing a challenging patient care situation, preparing for the boards, or studying for recertification.

Key Features

Addresses timely topics alongside foundational basic science for an in-depth and comprehensive understanding of the field
Contains thoroughly up-to-date content, including two new chapters: The Immune System: Implications for Anesthetic Management and Emergency Preparedness in Healthcare
Provides new content in key areas such as sustainability, global health equity, the effect of anesthetics on immune function, anesthesia for special populations, coverage of infectious diseases including COVID-19, and occupational exposure and safety
Offers state-of-the-art coverage of anesthetic drugs, guidelines for anesthetic practice and patient safety, new techniques, step-by-step instructions for patient management, the unique needs of pediatric patients, and much more—all highlighted by more than 1,200 full-color illustrations (300 new to this edition) for enhanced visual clarity
Includes 40+ video clips demonstrating patient positioning, ultrasound, echocardiograms, and other imaging, and anesthetic procedures in real time
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

About the author

Edited by Michael A. Gropper, MD, PhD, Distinguished Professor and Chair, Department of Anesthesia and Perioperative Care; Professor of Physiology; Investigator, Cardiovascular Research Institute, University of California, San Francisco, CA, USA; Lars I. Eriksson, MD, Professor and Academic Chair, Department of Anaesthesiology and Intensive Care Medicine, Karolinska University Hospital, Solna, Sweden; Lee A. Fleisher, MD, Robert Dunning Drips Professor and Chair of Anesthesiology and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Neal H. Cohen, MD, MPH, MS, Vice Dean, Affiliations and Compliance Professor Emeritus, Anesthesia and Perioperative Care and Medicine, UCSF School of Medicine, San Francisco, California, USA; Kate Leslie, MD, Staff Specialist, Head of Anesthesia Research, Royal Melbourne Hospital; Professor, Department of Anesthesiology, Monash University, Melbourne, Australia and Oluwaseun Johnson-Akeju, MD, Anesthetist-in-Chief, Henry Isaiah Dorr Associate Professor of Research and Teaching in Anaesthetics and Anaesthesia, Massachusetts General Hospital, Boston, Massachusetts, USA

VOLUME 1
SECTION I Introduction
1. The Scope of Modern Anesthetic Practice
2. Anesthesia and Global Health Equity
3. Perioperative Medicine
4. Informatics in Perioperative Medicine
5. Quality Improvement in Anesthesia Practice and Patient Safety
6. Human Behavior and Simulation in Anesthesia
7. Ethical Aspects of Anesthesia Care

SECTION II Anesthetic Physiology
8. Consciousness, Memory, and Anesthesia
9. Sleep Medicine
10. Cerebral Physiology and the Effects of Anesthetic Drugs
11. Neuromuscular Physiology and Pharmacology
12. Respiratory Physiology and Pathophysiology
13. Cardiac Physiology
14. Gastrointestinal and Hepatic Physiology, Pathophysiology, and Anesthetic Considerations
15. Renal Anatomy, Physiology, Pharmacology, and Evaluation of Function
16. Basic Principles of Pharmacology
17. Inhaled Anesthetics: Mechanisms of Action
18. Inhaled Anesthetic Uptake, Distribution, Metabolism, and Toxicity
19. Pulmonary Pharmacology of Inhaled Anesthetics
20. Inhaled Anesthetic Delivery Systems
21. Intravenous Anesthetics
22. Opioids
23. Intravenous Drug Delivery Systems
24. Pharmacology of Neuromuscular Blocking Drugs and Antagonists (Reversal Agents)
25. Local Anesthetics
26. Immune Implications of Anesthesia Care and Practice

SECTION III Anesthesia Management
27. Risk of Anesthesia
28. Preoperative Evaluation
29. Anesthetic Implications of Concurrent Diseases
30. Patient Positioning and Associated Risks
31. Neuromuscular Disorders and Other Genetic Disorders
32. Cardiovascular Monitoring
33. Perioperative Echocardiography and Point-of-Care Ultrasound (POCUS)
34. Implantable Cardiac Pulse Generators: Pacemakers and Cardioverter-Defibrillators
35. Neurophysiologic Monitoring
36. Monitoring the Brain’s Response to Anesthesia and Surgery
37. Respiratory Monitoring
38. Renal Pathophysiology and Treatment for Perioperative Ischemia and Nephrotoxic Injury
39. Neuromuscular Monitoring
40. Airway Management in the Adult
41. Spinal, Epidural, and Caudal Anesthesia
42. Peripheral Nerve Blocks and Ultrasound Guidance for Regional Anesthesia
43. Perioperative Fluid and Electrolyte Therapy
44. Perioperative Acid–Base Balance
45. Patient Blood Management: Transfusion Therapy
46. Patient Blood Management: Coagulation

VOLUME 2
SECTION IV Adult Subspecialty Management
47. Management of the Patient with Chronic Pain
48. Palliative Medicine
49. Anesthesia for Thoracic Surgery
50. Anesthesia for Cardiac Surgical Procedures
51. Anesthesia for Correction of Cardiac Arrhythmias
52. Anesthesia for Vascular Surgery
53. Anesthesia for Neurologic Surgery and Neurointerventions
54. Anesthesia for Bariatric Surgery
55. Anesthesia and the Renal and Genitourinary Systems
56. Anesthesia for Abdominal Organ Transplantation
57. Anesthesia for Organ Procurement
58. Anesthesia for Obstetrics
59. Anesthesia for Fetal Surgery and Other Fetal Therapies
60. Anesthesia for Orthopedic Surgery
61. Geriatric Anesthesia
62. Anesthesia for Trauma
63. Prehospital Care for Medical Emergencies and Trauma
64. Biologic, Natural, and Human-Induced Disasters: The Role of the Anesthesiologist
65. Anesthesia for Ophthalmic Surgery
66. Anesthesia for Otolaryngologic and Head–Neck Surgery
67. Anesthesia for Robotic Surgery
68. Ambulatory (Outpatient) Anesthesia
69. Non–Operating Room Anesthesia
70. Clinical Care in Extreme Environments: Physiology at High Altitude and in Space
71. Clinical Care in Extreme Environments: High Pressure, Immersion, Drowning, Hypo-, and Hyperthermia

SECTION V Pediatric Anesthesia
72. Pediatric Anesthesia
73. Anesthesia for Pediatric Cardiac Surgery
74. Regional Anesthesia in Children
75. Pediatric and Neonatal Critical Care

SECTION VI Postoperative Care
76. The Postanesthesia Care Unit
77. Acute Postoperative Pain
78. Perioperative Neurocognitive Disorders

SECTION VII Critical Care Medicine
79. Critical Care Anesthesiology
80. Neurocritical Care
81. Extracorporeal Membrane Oxygenation and Cardiac Devices
82. Cardiopulmonary Resuscitation and Advanced Cardiac Life Support

SECTION VIII Ancillary Responsibilities and Problems
83. Burn Management
84. Occupational Safety, Infection Control, and Substance Use Disorders
85. Emergency Preparedness in Health Care
86. Clinical Research
87. Interpreting the Medical Literature

Book Reviews

"Spanning 2740 pages across two weighty volumes, the textbook is literally and figuratively substantial. For those who want to spare their backs (or bookshelves), a digital version is available through Elsevier’s eBooks+ platform, offering features such as customisable layouts, annotation tools, and integrated videos on clinical techniques, including airway management, echocardiography, and ultrasound-guided procedures.... The format of Miller’s Anesthesia makes it ideal as a comprehensive study resource or reference text for in-depth reading, rather than a quick-access guide in the operating theatre. In that sense, it remains an important publication, particularly valuable for residents and practitioners in North America.... Ultimately, the 10th edition reaffirms Miller’s Anesthesia as an authoritative and expertly edited resource. It remains the gold standard reference for anaesthesia in North America." Review by Andrew F. Cumpstey, Jaideep J. Pandit and Eoin M. Kelleher, British Journal of Anaesthesia, September 2025

"The quintessential book for learning the science and practice of anesthesiology and has for years been the standard bearer for resident house staff and attending anesthesiologists." ©Doody’s Review Service, 2025, Joshua E. Insler, MD (Yale School of Medicine)

ISBN: 9780323935920

Page Count: 3016

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Anesthesiologists, anesthesiology residents and fellows