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Swaiman's Pediatric Neurology,

Edition 7 Principles and Practice

Editors: Edited by Stephen Ashwal, MD and Phillip L. Pearl, MD

Publication Date: 23 Apr 2025

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**Selected for 2025 Doody’s Core Titles® in Pediatrics and with "Essential Purchase" designation in Neurology**

For fifty years, experienced clinicians and physicians in training have relied on Swaiman’s cornerstone text as their #1 source for authoritative guidance in pediatric neurology. Swaiman's Pediatric Neurology: Principles and Practice, Seventh Edition, continues this tradition of excellence under the expert editorial direction of Drs. Stephen Ashwal and Phillip L. Pearl, along with a team of key leaders in the field who serve as associate and section editors in their areas of expertise. Thorough revisions—including new chapters, new videos, new editors, and expanded content—bring you up to date with this dynamic field.

Key Features

Contains new sections on global child neurology and environment and brain development and a greatly expanded section on neurogenetics, in addition to new chapters on autoimmune epilepsies, immune-mediated movement disorders, and more
Offers expanded online content, including additional figures, tables, and text, as well as new personal introductory videos by many chapter authors
Covers new, emerging, or controversial topics such as COVID-19, teleneurology, environment and brain development, immune-mediated disorders of the nervous system, functional neurological disorders in children, nonverbal learning disorders, and the pharmacological and future genetic treatment of neurodevelopmental disabilities
Provides authoritative coverage of perinatal acquired and congenital disorders, neurodevelopmental disabilities, extensive sections on pediatric epilepsy and movement disorders, nonepileptiform paroxysmal disorders, and disorders of sleep
Features nearly 3,000 line drawings, photographs, tables, and boxes that highlight the text, clarify key concepts, and make it easy to find information quickly
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

About the author

Edited by Stephen Ashwal, MD, Distinguished Professor of Pediatrics, Former Chief of the Division of Child Neurology and Pediatrics, Loma Linda University School of Medicine, Loma Linda, California, USA and Phillip L. Pearl, MD, Director of Epilepsy and Clinical Neurophysiology, William G. Lennox Chair and Professor of Neurology, Harvard Medical School, Boston, Massachusetts, USA

PART I: Clinical Evaluation
1. General Aspects of the Patient’s Neurologic History
2. Neurologic Examination of the Older Child
3. Neurologic Examination of Young Children (Ages 1–5 Years)
4. Neurologic Examination of Infants (Ages 0–1 Year)
5. Motor Signs
6. Vision Loss
7. Hearing Impairment
8. Vertigo
9. Taste and Smell
10. Neuropsychological Assessment

PART II: Care of the Child With Neurologic Disorders
11. Counseling Children With Neurologic Disorders and Their Families
12. Pediatric Neurorehabilitation Medicine
13. Pediatric Palliative Care, Pain, and Symptom Management
14. Practical Bioethics in Child Neurology
15. Transitional Care for Children With Neurologic Disorders
16. Practice Guidelines in Pediatric Neurology
17. Measurement of Health Outcomes in Pediatric Neurologic Disorders
18. Computer Resources, Artificial Intelligence, and Telemedicine
19. Education and Training of Child Neurologists and Workforce Issues

PART III: Neurodiagnostic Testing
20. Cerebrospinal Fluid Examination
21. Pediatric Neuroimaging
22. Pediatric Neurophysiologic Evaluation

PART IV: Global Child Neurology
23. Regional and Global Implications for Children’s Brain Health
24. Implementing Child Neurology Care in Resource-Limited Settings
25. Adaptation and Implementation of Guidelines at the Local Level

PART V: Neonatal Neurology
26. Neonatal Neuro-Intensive Care
27. Provoked Neonatal Seizures and Neonatal Onset Epilepsy
28. Hypoxic-Ischemic Brain Injury in the Term Newborn
29. Cerebrovascular Disorders in the Newborn
30. Neonatal Nervous System Trauma
31. Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury
32. Perinatal Metabolic Encephalopathies

PART VI: Environment and Brain Development
33. The Neural Exposome and Environmental Neuroscience
34. Adverse Childhood Experiences
35. The Neurological Impact of Prenatal Substance Exposure
36. Environmental Pollutants
37. Malnutrition, Nutrition, and Dietary Toxins
38. Poisoning and Drug-Induced Neurologic Diseases

PART VII: Congenital Structural Defects
39. Introduction to Human Brain Malformations
40. Disorders of Neural Tube Development
41. Disorders of Forebrain Development
42. Disorders of Cerebellar and Brainstem Development
43. Microcephaly and Megalencephaly: Disorders of Brain Size
44. Malformations of Cortical Development
45. Hydrocephalus, Cysts, and Cystic Malformations
46. Congenital Anomalies of the Skull
47. Prenatal Diagnosis of Structural Brain Anomalies

PART VIII: Neurogenetics
48. Neurogenetics in the Genome Era
49. Genetic Counseling in the Genomic Era
50. Chromosomes and Chromosomal Abnormalities
51. Single-Gene Abnormalities
52. Neurocutaneous Disorders
53. Emerging Gene-Based Pathways: Channelopathies (Epilepsy and Beyond)
54. Emerging Gene-Based Pathways: mTORopathies
55. Emerging Gene-Based Pathways: RASopathies
56. Emerging Gene-Based Pathways: Chromatin Remodeling Disorders
57. The Neuronal Ceroid Lipofuscinoses

PART IX: Metabolic Disorders
58. Approach to the Patient With a Metabolic Disorder
59. Aminoacidemias and Organic Acidemias
60. Urea Cycle Disorders
61. Diseases Associated With Primary Abnormalities in Carbohydrate Metabolism
62. Disorders of Glycosylation
63. Lysosomal Storage Diseases
64. Mitochondrial Diseases
65. Peroxisomal Disorders
66. Neurotransmitter-Related Disorders
67. Disorders of Vitamin Metabolism

PART X: Neurodevelopmental Disorders
68. Neurodevelopmental Disabilities: Conceptual Framework
69. Intellectual Developmental Disorder and Global Developmental Delay
70. Regressive and Degenerative Genetic Neurological Disorders
71. Developmental Encephalopathies
72. Developmental Language Disorders
73. Nonverbal Learning Disorders
74. Dyslexia
75. Attention-Deficit/Hyperactivity Disorder
76. Autism Spectrum Disorder
77. Cerebral Palsy
78. Developmental Coordination Disorder
79. Treatment of Neurodevelopmental Disorders
80. Neuropsychopharmacology

PART XI: Epilepsy
81. Overview of Seizures and Epilepsy in Children
82. Principles of Management and Outcome
83. Pathophysiology of Seizures and Epilepsy
84. Epilepsy Genetics
85. Febrile Seizures
86. Generalized Seizures
87. Focal and Multifocal Seizures
88. Myoclonic Seizures
89. Infantile Epileptic Spasms Syndrome
90. Status Epilepticus
91. Electroclinical Syndromes: Neonatal Onset
92. Electroclinical Syndromes: Infantile Onset
93. Electroclinical Syndromes: Childhood Onset
94. Electroclinical Syndromes: Adolescent Onset
95. Focal Structural Epilepsy
96. Acquired Epilepsies: Trauma, Stroke, and Tumors
97. Inherited Metabolic Epilepsies
98. Antiseizure Medication Therapy in Children
99. Epilepsy Surgery in the Pediatric Population
100. Neuromodulation in Epilepsy
101. Ketogenic Diets
102. Behavioral, Cognitive, and Social Implications of Childhood Epilepsy
103. Mortality in Children With Epilepsy

PART XII: Nonepileptiform Paroxysmal Disorders
104. Headache in Children and Adolescents
105. Breath-Holding Spells and Reflex Anoxic Seizures
106. Psychogenic Nonepileptic Seizures and Psychiatric Disorders
107. Functional Neurological Symptom Disorder in Children and Adolescents
108. Syncope and Postural Orthostatic Tachycardia Syndrome
109. Brief Resolved Unexplained Events, Apparent Life-Threatening Events, and Sudden Infant Death Syndrome

PART XIII: Disorders of Sleep
110. Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents
111. Nocturnal Paroxysmal Disorders
112. Disorders of Excessive Sleepiness

PART XIV: Disorders of Balance and Movement
113. The Cerebellum and the Hereditary Ataxias
114. Movement Disorders: An Overview
115. Paroxysmal Dyskinesias
116. Movement Disorders of Infancy
117. Drug-Induced Movement Disorders in Children
118. Tics and Tourette Syndrome

PART XV: White Matter Disorders
119. Genetic and Metabolic Disorders of the White Matter
120. Acquired Disorders Affecting the White Matter

PART XVI: Brain Injury and Disorders of Consciousness
121. Impairment of Consciousness and Coma
122. Traumatic Brain Injury in Children
123. Abusive Head Trauma
124. Hypoxic-Ischemic Encephalopathy in Infants and Older Children
125. Disorders of Intracranial Pressure
126. Spinal Cord Injury
127. Determination of Brain Death/Death by Neurologic Criteria in Infants and Children

PART XVII: Cerebrovascular Disease in Children
128. Arterial Ischemic Stroke in Infants and Children
129. Sinovenous Thrombosis
130. Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children
131. Cerebral Arteriopathies
132. Coagulation Disorders and Cerebrovascular Disease in Children

PART XVIII: Infections of the Nervous System
133. Bacterial Infections of the Nervous System
134. Viral Infections of the Nervous System
135. Fungal, Rickettsial, and Parasitic Diseases of the Nervous System
136. Neurologic Complications of Immunization

PART XIX: Immune-Mediated Disorders of the Nervous System
137. Diagnosis and Management of Pediatric Neuroimmunological Disorders
138. Autoimmune Encephalitis
139. Autoimmune-Associated Epilepsies
140. Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus, and Pediatric Acute Neuropsychiatric Syndrome
141. Immune-Mediated Cerebellar Disorders
142. Neurorheumatology

PART XX: Pediatric Neuro-Oncology
143. Pediatric Neuro-Oncology: An Overview
144. Medulloblastoma
145. Other Embryonal and Pineal Malignancies of the Central Nervous System
146. Ependymoma
147. Pediatric-Type Diffuse High-Grade Glioma
148. Pediatric Low-Grade Glioma
149. Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma
150. Atypical Teratoid/Rhabdoid Tumors
151. Central Nervous System Germ Cell Tumors
152. Craniopharyngiomas, Meningiomas, and Schwannomas
153. Pediatric Intradural Spinal Cord Tumors
154. Systemic Cancers and Central Nervous System Involvement
155. Treatment-Related Neurologic Sequelae of Pediatric Central Nervous System Tumors

PART XXI: Neuromuscular Disorders
156. Muscle and Nerve Development in Health and Disease
157. Diagnostic Testing in Children With Suspected Neuromuscular Disorders
158. Clinical Assessment of Pediatric Neuromuscular Disorders
159. The Floppy Infant
160. Classic Proximal Spinal Muscular Atrophy
161. Other Motor Neuron Diseases of Childhood
162. Genetic Peripheral Neuropathies
163. Acquired Peripheral Neuropathies
164. Inflammatory Neuropathies
165. Congenital Myasthenic Syndromes
166. Acquired Disorders of the Neuromuscular Junction
167. Duchenne and Becker Muscular Dystrophy
168. Congenital, Limb-Girdle, and Other Muscular Dystrophies
169. Congenital Myopathies
170. Metabolic Myopathies
171. Inflammatory Myopathies
172. Channelopathies: Myotonic Disorders and Periodic Paralysis
173. Multidisciplinary Management of Children With Neuromuscular Conditions

PART XXII: Systemic and Autonomic Nervous System Diseases
174. Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence
175. Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice
176. Disorders of Micturition and Defecation
177. Neurologic Disorders in Children With Heart Disease
178. Neurologic Disorders Associated With Renal Diseases
179. Neurologic Manifestations and Disorders Associated With Gastrointestinal Diseases

Index

Book Reviews

5 Stars! "...serves as a comprehensive guide to maintaining up-to-date learning and knowledge in child neurology.... [It] bridges the gap between what pediatric neurologists learned in training and what they need to know today [and] is designed to be the resource reached for when facing real clinical decisions, not just another reference gathering dust on the shelf.... The book successfully bridges the gap between comprehensive reference and practical clinical guide.... Each chapter feels integrated rather than simply collected, with cross-references that actually make sense and consistent approaches to differential diagnosis and management. The writing throughout is clear and accessible without sacrificing scientific rigor. Complex concepts are explained in ways that residents can grasp while providing the depth that seasoned practitioners need. The tables and figures are superb and I have already found myself bookmarking several for teaching purposes,... a must-have for all medical libraries, both in physical and ebook formats." Review by Yash Shah, MD MPH (Northwell Health), ©Doody's Review Service, 2025. Doody's Score: 99, 5 Stars!

Swaiman's Pediatric Neurology,

Editors: Edited by Stephen Ashwal, MD and Phillip L. Pearl, MD

Description

Key Features

About the author

Book Reviews