New
Gunderson and Tepper’s Clinical Radiation Oncology,
Edition 6Editors: Edited by Robert L. Foote, MD, Jeff M. Michalski, MD, MBA, FACR, FASTRO, Akila Viswanathan, MD, MPH, MSc and Joel E. Tepper, MD
Publication Date:
13 Jan 2026
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Expertly written and meticulously edited to ensure scientifically accurate, accessible content throughout, Gunderson and Tepper’s Clinical Radiation Oncology, 6th Edition, provides complete, multidisciplinary coverage of this complex and dynamic field. Concise, templated chapters cover the basic biology of oncologic disease processes as well as updated treatment algorithms, the latest clinical guidelines, and state-of-the-art techniques and modalities. User-friendly elements such as summarized key issues, full-color formatting, extensive use of tables and figures, and access to videos online make this reference an ideal resource for every member of the radiation oncology team.
Key Features
- Divides content into three distinct sections for quick access to information: Scientific Foundations, Techniques and Modalities, and Disease Sites. Disease Site chapters include overviews summarizing the most important issues and concluding discussions on controversies and problems
- Provides expert guidance on single-modality and combined-modality approaches, as well as outcome data including disease control, survival, and treatment tolerance
- Contains a new chapter on artificial intelligence in radiation, as well as up-to-date coverage of advancements in interventional radiology tumor ablation techniques and associated outcomes; updated guidance on using Intraoperative Radiation Therapy (IORT) as a radiation dose escalation tool; and increased coverage of proton therapy
- Features more than 1,000 images¿detailed anatomy drawings, radiographic images, and more - that provide outstanding visual support for every area of the text
- Covers key topics such as brachytherapy, precision radiation therapy, palliative radiotherapy, quality and safety, image-guided radiotherapy (IGRT), and stereotactic radiosurgery
- Includes access to videos on intraoperative irradiation, prostate brachytherapy, penile brachytherapy, and ocular melanoma
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
About the author
Edited by Robert L. Foote, MD, Hitachi Professor of Radiation Oncology Research, Mayo Clinic Alix School of Medicine, Department of Radiation Oncology
Chair, Mayo Clinic Rochester Cancer Coordinating Committee, Mayo Clinic Cancer Center; Jeff M. Michalski, MD, MBA, FACR, FASTRO, Carlos A. Perez Distinguished Professor, Vice-Chairman and Director for Clinical Programs, Washington University School of Medicine
Siteman Cancer Center, Department of Radiation Oncology; Akila Viswanathan, MD, MPH, MSc, Director, Johns Hopkins Radiation Oncology and Molecular Radiation Sciences, Professor of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine and Joel E. Tepper, MD, Hector MacLean Distinguished Professor of Cancer Research, Department of Radiation Oncology, University of North Carolina Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
SECTION 1 Scientific Foundations of Radiation Oncology
PART A Radiobiology
1. The Biological Basis of Radiation Oncology
2. Molecular and Cellular Biology
3. Dose-Response Modifiers in Radiation Therapy
4. Interaction of Chemotherapy and Radiation
5. Modulation of Radiation Response with Molecularly Targeted Therapy
6. Cancer Immunity and Radiation
PART B Physics
7. Radiation Oncology Physics
8. Radiation Physics: Stereotactic
9. Radiation Physics: Charged Particle Therapy
10. Artificial Intelligence in Clinical Radiation Oncology
PART C related cancer Disciplines
11. Surgical Principles
12. Principles of Systemic Cancer Therapy
13. Imaging in Oncology
14. Nuclear Medicine and PET
15. Tumor Ablation in Interventional Radiology
16. Overview of Oncology Clinical Trial Design
17. Health Services Research in Radiation Oncology
18. Radiation Therapy in the Older Adult
19. Palliative Radiation Medicine
20. Late Effects After Radiation
SECTION 2 Techniques and Modalities
21. Quality and Safety in Radiation Oncology
22. Principles and Practice of Brachytherapy
23. Intensity-Modulated and Image-Guided Radiotherapy
24. Intraoperative Irradiation
25. Total Body Irradiation
26. Charged Particle Radiotherapy
27. Radiopharmaceutical Therapy
28. Radiotherapy and Immunotherapy
29. Stereotactic Irradiation: CNS Tumors
30. Stereotactic Body Irradiation: Extracranial Tumors
31. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung
SECTION 3 Disease Sites
PART A central nervous System tumors
32. Central Nervous System Tumors: Overview
33. Low-Grade Gliomas
34. High-Grade Gliomas
35. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas
36. Pituitary Tumors and Craniopharyngiomas
37. Spinal Cord Tumors
38. Ocular, Orbital, and Optic Nerve Tumors
PART B Head and neck tumors
39. Overview
40. Oral Cavity
41. Oropharyngeal Cancer
42. Nasopharyngeal Carcinoma
43. Larynx and Hypopharynx Cancer
44. Sinonasal Cancer
45. Salivary Gland Malignancies
46. Thyroid Cancer
47. Unknown Head and Neck Primary Site
48. Management of the Neck
49. Cutaneous Carcinoma
50. Melanoma
PART C thoracic neoplasms
51. Overview
52. Small-Cell Lung Cancer
53. Non-small Cell Lung Cancer
54. Uncommon Thoracic Tumors
PART D Gastrointestinal tumors
55. Gastrointestinal Tumors Overview
56. Esophagus-Gastric Cancer
57. Pancreatic Cancer
58. Hepatobiliary Cancer
59. Colon Cancer
60. Rectal Cancer
61. Anal Carcinoma
PART E Genitourinary tumors
62. Overview
63. Prostate Cancer
64. Bladder Cancer
65. Testicular Cancer
66. Kidney and Ureteral Carcinoma
67. Penile Cancer
PART F Gynecologic tumors
68. Overview
69. Cervical Cancer
70. Endometrial Cancer
71. Cancers of the Vulva and Vagina
72. Ovarian Cancer
PART G Breast cancer
73. Overview
74. Noninvasive Breast Cancer
75. Breast Cancer: Stages I and II
76. Locally Advanced and Inflammatory Breast Cancer
PART H Sarcoma and Benign Disease
77. Soft-Tissue Sarcoma
78. Benign Diseases
PART I childhood cancers
79. Overview
80. Central Nervous System Tumors in Children
81. Pediatric Soft Tissue Sarcomas
82. Pediatric Sarcomas of Bone
83. Wilms’ Tumor
84. Retinoblastoma
85. Neuroblastoma
86. Pediatric Leukemia and Lymphoma
87. Pediatric Hodgkin Lymphoma
88. Rare Pediatric Tumors
PART J Lymphoma and Hematologic Malignancies
89. Overview
90. Hodgkin Lymphoma
91. Non-Hodgkin Lymphoma
92. Multiple Myeloma and Other Plasma Cell Neoplasms
93. Mycosis Fungoides
INDEX
PART A Radiobiology
1. The Biological Basis of Radiation Oncology
2. Molecular and Cellular Biology
3. Dose-Response Modifiers in Radiation Therapy
4. Interaction of Chemotherapy and Radiation
5. Modulation of Radiation Response with Molecularly Targeted Therapy
6. Cancer Immunity and Radiation
PART B Physics
7. Radiation Oncology Physics
8. Radiation Physics: Stereotactic
9. Radiation Physics: Charged Particle Therapy
10. Artificial Intelligence in Clinical Radiation Oncology
PART C related cancer Disciplines
11. Surgical Principles
12. Principles of Systemic Cancer Therapy
13. Imaging in Oncology
14. Nuclear Medicine and PET
15. Tumor Ablation in Interventional Radiology
16. Overview of Oncology Clinical Trial Design
17. Health Services Research in Radiation Oncology
18. Radiation Therapy in the Older Adult
19. Palliative Radiation Medicine
20. Late Effects After Radiation
SECTION 2 Techniques and Modalities
21. Quality and Safety in Radiation Oncology
22. Principles and Practice of Brachytherapy
23. Intensity-Modulated and Image-Guided Radiotherapy
24. Intraoperative Irradiation
25. Total Body Irradiation
26. Charged Particle Radiotherapy
27. Radiopharmaceutical Therapy
28. Radiotherapy and Immunotherapy
29. Stereotactic Irradiation: CNS Tumors
30. Stereotactic Body Irradiation: Extracranial Tumors
31. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung
SECTION 3 Disease Sites
PART A central nervous System tumors
32. Central Nervous System Tumors: Overview
33. Low-Grade Gliomas
34. High-Grade Gliomas
35. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas
36. Pituitary Tumors and Craniopharyngiomas
37. Spinal Cord Tumors
38. Ocular, Orbital, and Optic Nerve Tumors
PART B Head and neck tumors
39. Overview
40. Oral Cavity
41. Oropharyngeal Cancer
42. Nasopharyngeal Carcinoma
43. Larynx and Hypopharynx Cancer
44. Sinonasal Cancer
45. Salivary Gland Malignancies
46. Thyroid Cancer
47. Unknown Head and Neck Primary Site
48. Management of the Neck
49. Cutaneous Carcinoma
50. Melanoma
PART C thoracic neoplasms
51. Overview
52. Small-Cell Lung Cancer
53. Non-small Cell Lung Cancer
54. Uncommon Thoracic Tumors
PART D Gastrointestinal tumors
55. Gastrointestinal Tumors Overview
56. Esophagus-Gastric Cancer
57. Pancreatic Cancer
58. Hepatobiliary Cancer
59. Colon Cancer
60. Rectal Cancer
61. Anal Carcinoma
PART E Genitourinary tumors
62. Overview
63. Prostate Cancer
64. Bladder Cancer
65. Testicular Cancer
66. Kidney and Ureteral Carcinoma
67. Penile Cancer
PART F Gynecologic tumors
68. Overview
69. Cervical Cancer
70. Endometrial Cancer
71. Cancers of the Vulva and Vagina
72. Ovarian Cancer
PART G Breast cancer
73. Overview
74. Noninvasive Breast Cancer
75. Breast Cancer: Stages I and II
76. Locally Advanced and Inflammatory Breast Cancer
PART H Sarcoma and Benign Disease
77. Soft-Tissue Sarcoma
78. Benign Diseases
PART I childhood cancers
79. Overview
80. Central Nervous System Tumors in Children
81. Pediatric Soft Tissue Sarcomas
82. Pediatric Sarcomas of Bone
83. Wilms’ Tumor
84. Retinoblastoma
85. Neuroblastoma
86. Pediatric Leukemia and Lymphoma
87. Pediatric Hodgkin Lymphoma
88. Rare Pediatric Tumors
PART J Lymphoma and Hematologic Malignancies
89. Overview
90. Hodgkin Lymphoma
91. Non-Hodgkin Lymphoma
92. Multiple Myeloma and Other Plasma Cell Neoplasms
93. Mycosis Fungoides
INDEX
ISBN:
9780443114762
Page Count:
1648
Illustrations
:
Approx. 150 illustrations (100 in full color)
Retail Price
:
Radiation oncologists – practitioners, fellows, and residents