Microbiology & Immunology Case Reports,

Edition 1

Editors: Edited by Ken S. Rosenthal, PhD, Emily Blodget, MD, Susan Butler-Wu, PhD, Wendy Gould, MD, Minto Porter, MD, Raj Dasgupta, MD, FACP, FCCP, FAASM, Raj Dasgupta, MD, FACP, FCCP, FAASM and Michele Koolaee, MD

Publication Date: 20 Jul 2026

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Microbiology and Immunology Case Reports: Beyond the Pearls is a case-based reference that covers the key material essential for USMLE and exam preparation. Focusing on the practical information you need to know, it teaches how to analyze a clinical vignette, sharpening your clinical decision-making skills and helping you formulate an evidence-based approach to realistic patient scenarios.

Key Features

Covers core, high-yield content on microbiology and immunology in a practical, concise, easy-to-read manner
Features case scenarios, clinical pearls, tables, imaging, microscopic and gross illustrations, as well as Beyond the Pearls tips and secrets (all evidence-based with references) that provide deep coverage of core material
Teaches how to learn with a patient-focused, clinical approach
Includes questions throughout the case that put you in the physician’s place and demonstrate the decision making that is needed both in the hospital and on exams
Cases have been carefully chosen and cover scenarios and questions frequently encountered on the USMLE, shelf exams, and clinical practice, integrating both basic science and clinical pearls
Written and edited by experienced teachers and clinicians; each case has been reviewed by board certified attending/practicing physicians and basic scientists
Case Reports: Beyond the Pearls titles are ideal for all medical students, especially those in case-based, problem-based, or integrated courses, and during clinical rotations
An eBook version is included with purchase. The eBook allows you to access all of the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud

About the author

Edited by Ken S. Rosenthal, PhD, Adjunct Professor Infectious Diseases University of Georgia College of Veterinary Medicine; Professor of Immunology Augusta University, University of Georgia Medical Partnership Athens, Georgia; Emeritus Professor Northeastern Ohio Medical University Rootstown, Ohio; Emily Blodget, MD, Clinical Associate Professor of Medicine (Clinician Educator), ACGME Infectious Diseases Fellowship Program Director, Co-Interim Chief for the Division of Infectious Diseases, School, Keck School of Medicine of USC, USA; Susan Butler-Wu, PhD, Director of Clinical Microbiology, LAC+USC Medical Center; Associate Professor of Clinical Pathology; Keck School of Medicine of USC, Los Angeles, CA, USA; Wendy Gould, MD, Attending Physician, Allergy and Clinical Immunology, Allergy and Immunology, Sussman Allergy, Toronto, Ontario, Canada; Minto Porter, MD, Allergy, Asthma, and Immunology, Essentia Health, Brainerd, USA; Raj Dasgupta, MD, FACP, FCCP, FAASM, Associate Professor of Clinical Medicine, University of California, Riverside School of Medicine; Associate Program Director of Internal Medicine Residency, Huntington Health, Pasadena, California, USA; Raj Dasgupta, MD, FACP, FCCP, FAASM, Associate Professor of Clinical Medicine, University of California, Riverside School of Medicine; Associate Program Director of Internal Medicine Residency, Huntington Health, Pasadena, California, USA and Michele Koolaee, MD, Assistant Professor of Clinical Medicine, Division of Rheumatology, Keck School of Medicine of the University of Southern California, Los Angeles, California

Introduction—Microbiology
Introduction—Immunology
SECTION 1 Microbiology
PART A Bacteria
Chapter 1 A 28-Year-Old Female With Fever and Abdominal Pain
Chapter 2 A 25-Year-Old With Fever and Abdominal Pain After Returning From Travel
Chapter 3 A 48-Year-Old Female With Abdominal Cramping and Painful Diarrhea
Chapter 4 A 72-Year-Old Female With Diarrhea and Severe Abdominal Pain
Chapter 5 A 49-Year-Old Woman With Sore Throat and Fever
Chapter 6 A 68-Year-Old Male With Fever, Cough, and Worsening Dyspnea
Chapter 7 A 35-Year-Old Male Presents With a Seizure
Chapter 8 A 21-Year-Old Male With Pharyngitis
Chapter 9 A 70-Year-Old-Female With Fevers and Chills
Chapter 10 A 56-Year-Old Male With Fever, Headache, and Rash
Chapter 11 A 62-Year-Old Female With Flank Pain and Fevers
Chapter 12 A 54-Year-Old Homeless Male With Fevers, Chills, and Shortness of Breath
Chapter 13 A 43-Year-Old Female Presents to the Urgent Care With a 3-Day History of Sore Throat and Pain When Swallowing
Chapter 14 An 83-Year-Old Female With Generalized Weakness, Fever, and Altered Mentation
Chapter 15 A 42-Year-Old Male With Low Back Pain
Chapter 16 A 20-Year-Old Male With Penile Discharge
Chapter 17 A 57-Year-Old With History of Chronic Lymphocytic Leukemia Presenting With 2 Weeks of Fever, Cough, and Dyspnea
Chapter 18 A 23-Year-Old Female With Hemoptysis
Chapter 19 A 66-Year-Old Female With 2 Years of Productive Cough, Dyspnea, and Malaise
PART B Virus
Chapter 20 An 11-Month-Old Girl With Fever and a Rash
Chapter 21 A 33-Year-Old Woman With Vomiting and Diarrhea After a Cruise
Chapter 22 A 39-Year-Old-Male With Right Upper Quadrant Pain and Hematochezia
Chapter 23 A 48-Year-Old Male With Nonproductive Cough, Dyspnea, and Loss of Smell
Chapter 24 A 30-Year-Old Female With Malaise, Cough, and Myalgias
Chapter 25 A 42-Year-Old Female With Odynophagia
Chapter 26 A 16-Year-Old Female With Sore Throat
Chapter 27 A 34-Year-Old Female With Diarrhea
Chapter 28 A 48-Year-Old Male With Sudden Onset of Fever, Headache, and Confusion
Chapter 29 A 38-Year-Old HIV Patient With Various Nonspecific Symptoms
PART C Fungus
Chapter 30 A 57-Year-Old Female With Cough and Weight Loss
Chapter 31 A 55-Year-Old Woman With Rheumatoid Arthritis on Immunosuppressants Presents With Cough, Dyspnea, and Pleuritic Chest Pain
Chapter 32 A 21-Year-Old Male With Hemoptysis
Chapter 33 A 73-Year-Old-Male With a Painful Knee
PART D Parasite
Chapter 34 A 45-Year-Old Male With Prolonged Diarrhea
Chapter 35 A 70-Year-Old Female With Abdominal Pain
Chapter 36 A 40-Year-Old Immunocompromised Male With Ring-Enhancing Brain Lesions
Chapter 37 A 35-Year-Old Male Returning From Travel With Fever and Headache
Chapter 38 A 45-Year-Old Male With Heart Failure and Cardiomyopathy
SECTION 2 Immunology
Chapter 39 A 6-Year-Old Boy With Fever, Cough, and Shortness of Breath
Chapter 40 A 20-Month-Old Girl With Recurrent Infections
Chapter 41 A 25-Year-Old Female With a Diffuse, Itchy Rash, Fatigue, and Joint Pain
Chapter 42 A 7-Month-Old Boy Presents With Chronic Diarrhea and Failure to Thrive
Chapter 43 A 24-Year-Old Female Presents With Chronic Rhinitis, Sinus Congestion, and Recurrent Sinusitis
Chapter 44 A 50-Year-Old Male Establishing Care
Chapter 45 Four-Day-Old Boy Presents With Lethargy, Poor Feeding, and Craniofacial Abnormalities
Chapter 46 A 4-Month-Old Boy With Bloody Diarrhea and Eczema
Chapter 47 A 33-Year-Old Pregnant Female With Fever, Malaise, and Myalgia
Chapter 48 A 66-Year-Old Man Is Found by Paramedics With Hives, Hypotension, and Loss of Consciousness
Chapter 49 A 6-Year-Old Girl With Wheezing, Lip Swelling, and Vomiting
Chapter 50 A 29-Year-Old Male With Hemoptysis
Chapter 51 A 12-Year-Old Boy With Fever, Arthralgia, and Rash
Chapter 52 A 14-Year-Old Boy With Weeping, Pruritic Lesions on Lower Extremities
Chapter 53 A 7-Year-Old Boy With Arthralgias, Abdominal Pain, and Palpable Purpura
Chapter 54 A 67-Year-Old Male With Malaise and Fever After a Kidney Transplant
Chapter 55 A 4-Month-Old Infant With a History of Severe Combined Immunodeficiency Who Underwent Allogeneic Stem Cell Transplant and Presents With Pruritic Morbilliform Rash and Diarrhea
Chapter 56 A 4-Year-Old Boy Presents With Persistent Rash and Chronic Pruritis
Chapter 57 A 4-Year-Old Boy With Burning Sensation in the Chest and Abdominal Pain
Chapter 58 A 42-Year-Old Female Presents to the Emergency Department With Generalized Pruritus