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Crash Course – your effective every-day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have the essential information you need in one place to excel on your course and achieve exam success.
A winning formula now for over 20 years, each series volume has been fine-tuned and fully updated – with an improved full-colour layout tailored to make your life easier. Especially written by senior students or junior doctors – those who understand what is essential for exam success – with all information thoroughly checked and quality assured by expert Faculty Advisers, the result are books which exactly meet your needs and you know you can trust.
This volume concisely brings together the wide range of skills needed for interpreting or conducting medical research and audit. It starts with the basics of medical data analysis and interpretation, followed by how to critically review published studies and even extends to advice on career advancement including CV writing, securing academic opportunities and teaching. This book will allow you to build competence and confidence in the world of medical research.
- Provides the exam syllabus in one place - saves valuable revision time
 - Written by senior students and recent graduates - those closest to what is essential for exam success
 - Quality assured by leading Faculty Advisors - ensures complete accuracy of information
 - Features the ever popular 'Hints and Tips' boxes and other useful aide-mémoires - distilled wisdom from those in the know
 - Updated self-assessment section matching the latest exam formats – confirm your understanding and improve exam technique fast
 
About the author
By Amit Kaura, MSc (Dist), BSc (Hons), MB ChB, MRCP (UK), AFHEA, AMInstLM, Specialist Registrar in Cardiology, Imperial College Healthcare NHS Trust; NIHR Academic Clinicl Fellow in Cardiology, Imperial College London; National Heart and Lung Institute, Hammersmith Hospital, London UK; Darrel Francis; Shreelata T Datta, MD MRCOG LLM MBBS BSc (Hons), Associate Clinical Dean and Consultant Obstetrician and Gynaecologist at King's College Hospital, London, UK and Philip Xiu, MA (Cantab), MB BChir, MRCP, MRCGP, MScClinEd, FHEA, MAcadMEd, RCPathME, Honorary Senior Lecturer Leeds University School of Medicine PCN Educational Lead Medical Examiner Leeds Teaching Hospital Trust Leeds, UKSection 1 The essentials for career success
1    An introduction to research, audit and teaching  
Book purpose 
Research methodology
Audit and its loop
Teaching theory and practice
The essentials for career success
Further reading
2    Evidence-based medicine
What is evidence-based medicine?
Formulating clinical questions
Identifying relevant evidence
The search strategy
Search terms
Reviewing the search strategy
Critically appraising the evidence
Evaluating performance
Creating guideline recommendations
Further reading
3    How to get involved
Opportunities for research
Types of projects
Identifying the gap in the evidence
Finding a research supervisor/research group
Project funding
Advice for someone considering a career in academic medicine
Further reading
4    Presenting your research findings
Submitting an abstract for presentation
Selecting the right conference
Writing an abstract 
Poster presentations 
Oral presentations 
Answering audience questions 
Further reading 
5    Publishing your findings 
Writing up a research study manuscript 
Submitting a manuscript for publication 
Dealing with a rejected manuscript 
Further reading 
6    Writing a successful curriculum vitae 
Is a curriculum vitae necessary? 
What is a curriculum vitae? 
Writing an effective curriculum vitae 
Style and formatting 
Common mistakes 
Further reading 
Section 2 Research methodology  
7    Handling data   
Types of variables 
Types of data 
Displaying the distribution of a single variable 
Displaying the distribution of two variables 
Describing the frequency distribution: central tendency 
Describing the frequency distribution: variability 
Theoretical distributions 
Transformations 
Choosing the correct summary measure 
Further reading 
8    Investigating hypotheses 
Hypothesis testing 
Choosing a sample 
Extrapolating from sample to population 
Comparing means and proportions: confidence intervals 
The P-value 
Statistical significance and clinical significance 
Statistical power 
References 
Further reading 
9    Systematic review and meta-analysis 
Why do we need systematic reviews? 
Evidence synthesis 
Meta-analysis 
Presenting meta-analyses 
Evaluating meta-analyses 
Key example of a meta-analysis 
Reporting a systematic review 
References 
Further reading 
10  Research design  
Obtaining data 
Interventional studies 
Observational studies 
Clinical trials 
Bradford-Hill criteria for causation 
Choosing the right study design 
Further reading 
11  Randomized controlled trials 
Why choose an interventional study design? 
Parallel randomized controlled trial 
Confounding, causality and bias 
Interpreting the results 
Types of randomized controlled trials 
Key example of a randomized controlled trial 
Reporting a randomized controlled trial 
References 
Further reading 
12  Cohort studies 
Study design 
Interpreting the results 
Confounding, causality and bias 
Advantages and disadvantages 
Key example of a cohort study 
References 
Further reading 
13  Case–control studies  
Study design 
Interpreting the results 
Case study: risk of constrictive pericarditis
after acute pericarditis 
Confounding, causality and bias 
Key example of a case–control study 
References 
Further reading 
14  Measures of disease occurrence and
cross-sectional studies  
Measures of disease occurrence 
Study design 
Interpreting the results 
Confounding, causality and bias 
Key example of a cross-sectional study 
References 
Further reading 
15  Ecological studies 
Study design 
Interpreting the results 
Sources of error in ecological studies 
Key example of an ecological study 
References 
Further reading 
16  Case report and case series  
Background 
Conducting a case report 
Conducting a case series 
Critical appraisal of a case series 
Key examples of case reports 
Key example of a case series 
References 
Further reading 
17  Qualitative research  
Study design 
Organizing and analysing the data 
Validity, reliability and transferability 
Advantages and disadvantages 
Key example of qualitative research 
References 
Further reading 
18  Confounding  
What is confounding? 
Assessing for potential confounding factors 
Controlling for confounding factors 
Reporting and interpreting the results 
Key example of study confounding 
References 
Further reading 
19  Screening, diagnosis and prognosis 
Screening, diagnosis and prognosis 
Screening tests 
Example of a screening test using likelihood ratios 
Diagnostic tests 
Evaluating the performance of a diagnostic test 
The diagnostic process 
Example of a diagnostic test using predictive values 
Bias in diagnostic studies 
Prognostic tests 
References 
Further reading 
20  Statistical techniques 
Choosing appropriate statistical tests 
Comparison of one group to a hypothetical value 
Comparison of two groups 
Comparison of three or more groups 
Measures of association 
Further reading 
21  Economic evaluation   
What is health economics? 
Economic question and study design 
Cost-minimization analysis 
Cost-utility analysis 
Cost-effectiveness analysis 
Cost–benefit analysis 
Sensitivity analysis 
Further reading 
22  Critical appraisal checklists 
Critical appraisal 
Critical appraisal checklist: systematic reviews and meta-analyses 
Critical appraisal checklist: randomized controlled trials 
Critical appraisal checklist: diagnostic studies 
Critical appraisal checklist: qualitative studies 
Further reading 
23  Crash course in statistical formulae  
Describing the frequency distribution 
Extrapolating from ‘sample’ to ‘population’ 
Study analysis 
Test performance 
Economic evaluation 
Further reading 
Section 3 Audit and its loop: the modern approach to improving healthcare practice 
24  Clinical audit  
An introduction to clinical audit 
Planning the audit 
Choosing the standards 
Audit protocol 
Defining the sample 
Data collection 
Analysing the data 
Evaluating the findings 
Implementing change 
Example of a clinical audit 
Further reading 
25  Quality improvement 
Quality improvement versus audit 
The model for quality improvement 
The aim statement 
Measures for improvement 
Developing the changes 
The plan-do-study-act  cycle 
Repeating the cycle 
Example of a quality improvement project 
Further reading 
Section 4 Teaching Theory and Practice   
26  Medical education 
Introduction 
Learning perspectives/theories 
Optimizing learning 
Further reading 
27  Designing a teaching session and teaching programme   
Effective teaching session design 
Setting objectives 
Setting up a teaching programme 
Further reading 
28  Teaching methods 
Teaching small groups 
Teaching in the clinical environment 
Teaching large groups/lecturing 
Further reading 
29  Teaching materials  
The purpose of teaching materials 
Different types of teaching materials 
Social media 
Factors influencing the type of teaching material to use 
Creating effective teaching materials 
Further reading 
30  Evaluation, assessment and feedback  
Evaluation 
Assessment 
Feedback 
References 
Further reading 
31  Dealing with the student in difficulty 
Recognition 
Consultation 
Interventions and follow-up 
Further reading