The book provides a detailed overview of how the immune system works, covers physiology, innate and adaptive immunity and the immune system in health and disease. Readers will learn how to assess a patient with an immune problem and understand from first principles the diagnosis and management of immune disorders.
This popular book is an ideal companion for medical school courses and has been fully updated to include the latest science on immunotherapies.
Key Features
- Clear and concise – designed with the needs of busy medical students in mind – just the right amount of detail for your course
- Covers the latest scientific and clinical knowledge in the field
- Detailed illustrations help the reader grasp the concepts of immunology
- Detailed clinical cases demonstrate real-world applications
- Technical boxes point out important scientific advances
- End-of-chapter checklists of learning points facilitate review
- An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
New Features
- Updates in basic science
- New immunotherapies added e.g. CAR-T
- Updates on inborn errors of immunity and acquired immune disorders
Section 1: Introduction
1. Introduction to the Immune System
2. Basic Concepts and Components of the Immune System
Section 2: Antigen-Recognition Molecules
3. Introduction to Antigen Recognition
4. Antigens and Antibody Structure
5. Antibody-Antigen Interaction
6. Antibody Diversity
7. The T-Cell Receptor
8. Major Histocompatibility Complex
9. Review of Antigen Recognition
Section 3: Physiology
10. Antigen Processing and Presentation
11. Lymphocyte Activation
12. Hematopoiesis
13. The Organs and Tissues of the Immune System
14. B-Cell Development
15. T-Cell Development
16. T-Cell Interactions and T-Cell Help
17. Immunological Memory and Homeostasis
18. Regulation of the Immune System
19. Brief Review of Immune Physiology
Section 4: Innate Immunity
20. Constitutive Defenses Including Complement
21. Phagocytes
22. Killing in the Immune System
23. Inflammation
24. Cytokines in the Immune System
Section 5: Immune System in Health and Disease
25. Infections and Vaccines
26. Hypersensitivity Reactions
27. Immediate Hypersensitivity (Type I): Allergy
28. How Autoimmune Disease Develops
29. Antibody-Mediated Hypersensitivity (Type II)
30. Immune Complex Disease (Type III Hypersensitivity)
31. Delayed Hypersensitivity (Type IV) and Review of Hypersensitivity Reactions
32. Primary Immunodeficiency
33. Secondary Immunodeficiency
34. Transplantation
35. Tumor Immunology
36. Bio Pharmaceuticals
Glossary
Index
