Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who’s who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you’ll need to offer your patients the best possible care.
Key Features
- Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers.
- Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians.
- Diagnose AIDS manifestations confidently by comparing them to clinical images.
- Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness.
- Efficiently review essential data through numerous at-a-glance tables.
New Features
- Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings.
- Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine.
Contents
Preface vii
Contributors ix
Acknowledgments xv
SECTION 1: Epidemiology and biology of HIV infection
1 The global epidemiology of HIV/AIDS 3
Irum Zaidi, Kevin M De Cock
2 The origins and diversification of HIV 15
Michael Worobey, Guan-Zhu Han
3 Molecular biology of HIV: implications for new therapies 25
Warner C Greene, B Matija Peterlin, Matthew H Stremlau
4 The immune response to HIV 45
Clive M Gray, Pamela Gumbi, Lycias Zembe, Mopo Radebe, Bruce Walker
5 Viral and host determinants of HIV-1 disease progression 59
Danie¨lle van Manen, Ange´lique B van ’t Wout, Hanneke Schuitemaker
6 Acute HIV infection 77
Anthony D Kelleher, David A Cooper
7 Biology of HIV-1 transmission 89
Julie Overbaugh
SECTION 2: Prevention, diagnosis, and treatment of HIV infection
8 The design of a global HIV vaccine 97
Jerome H Kim, Nelson L Michael
9 HIV prevention 113
Salim S Abdool Karim
10 Laboratory testing for HIV infection 123
James C Shepherd, Oliver Laeyendecker, Thomas C Quinn
11 Overview of antiretroviral therapy 133
Susa Coffey, Paul A Volberding
12 Development and transmission of HIV drug resistance 155
Mark A Wainberg, Gerasimos J Zaharatos
13 Pharmacology of antiretroviral drugs 169
Concepta Merry, Charles W Flexner
14 Complications resulting from antiretroviral therapy for HIV infection 177
David Nolan, Simon Mallal, Peter Reiss
SECTION 3: Diseases associated with HIV infection
15 Oral complications of HIV infection 195
John S Greenspan, Deborah Greenspan
16 Ocular manifestations of AIDS 207
James P Dunn
17 Global HIV and dermatology 219
Toby Maurer, Robert Michelleti
18 Gastrointestinal disorders in HIV including diarrhea 237
Marie-Louise C Vachon, Douglas T Dieterich
19 Primary neurological manifestation of HIV/AIDS 249
David B Clifford, Mengesha A Teshome
20 Psychiatric barriers and the international AIDS epidemic 257
Chiadi U Onyike, Andrew F Angelino,
Glenn J Treisman
21 Cardiovascular complications of HIV infection 267
Rakesh K Mishra
22 Endocrine complications of HIV infection 275
Steven A Taylor, Carl Grunfeld,
Morris Schambelan
23 Renal complications of HIV infection 287
Jula K Inrig, Lynda A Szczech,
Trevor E Gerntholtz, Paul E Klotman
24 Pneumocystis pneumonia 297
Robert J Blount, J Lucian Davis,
Laurence Huang
25 Other HIV-related pneumonias 313
John G Bartlett
26 HIV-associated tuberculosis 325
Leyla Azis, Edward C Jones-Lo´pez,
Jerrold J Ellner
27 Disseminated Mycobacterium avium complex and other atypical mycobacterial infections 349
Mark A Jacobson
28 Candida in HIV infection 359
William G Powderly
29 Cryptococcosis and other fungal infections
(histoplasmosis and coccidioidomycosis)
in HIV-infected patients 369
Kathleen R Page, Richard E Chaisson,
Merle Sande
30 Infection due to Penicillium marneffei 389
Thira Sirisanthana, Khuanchai Supparatpinyo
31 AIDS-associated toxoplasmosis 397
Pablo A Moncada, Jose G Montoya
32 Hepatitis virus infections 411
Marion G Peters, Monika Sarkar
33 Bartonella infections in HIV-infected individuals 421
Jane E Koehler
34 Management of herpesvirus infections
(cytomegalovirus, herpes simplex virus, and varicella-zoster virus) 433
W Lawrence Drew, Kim S Erlich
35 HIV-associated malignancies 455
Ronald T Mitsuyasu
36 STDs and syphilis 467
Elysia Larson, Jeffrey D Klausner
SECTION 4: Prevention and management
37 Prevention of mother-to-child transmission of HIV-1 485
Lynne M Mofenson
38 Managing HIV infection in children and adolescents 509
Elizabeth H Doby, Andrew T Pavia
39 Special issues regarding women with HIV infection 521
Ruth M Greenblatt, Monica Gandhi
40 HIV disease among substance users:
treatment issues 537
R Douglas Bruce, Frederick L Altice,
Gerald Friedland
41 The HIV-infected international traveler 551
Malcolm John
Index 561
"In addition to the most important aspects of HIV infection, the book also covers global epidemiology, a real plus. Readers will be delighted with chapters on the biology of the virus, HIV prevention, antiretroviral therapy, and antiretroviral pharmacology. Much of the book is devoted to chapters on diseases associated with HIV infection. Special chapters detail management of mother-to-child transmission, adolescents, substance abuse, and travel medicine in the setting of HIV infection. This book is published in both print and electronic formats. The editors note that it is offered in a version for more resource-rich settings and in an overlapping but distinct version for "the resource-constrained 'South.
There is no other book available that provides such an amount of detail in a compendium format. It is an excellent resource that will satisfy most readers." - Uriel Sandkovsky, MD, FACP(University of Nebraska Medical Center) Doody 4 stars
"This is a comprehensive resource for infectious diseases physicians working in the developed and developing world. It’s authored by a veritable 'who’s who of global expertise' - the chapters stand out as they are written by real experts." - BMA Book Awards 2008 - Commended
978-1-4377-2702-9, Long, Pickering & Prober: Principles and Practice of Pediatric Infectious Disease, Expert Consult Basic, 4e,
0-323-06813-8, 978-0-323-06813-0, Auerbach: Medicine for the Outdoors, The Essential Guide to Emergency Medical Procedures and First Aid, 5e, Jun-2009
978-0-323-07942-6, Johns Hopkins Hospital, Arcara & Tschudy: The Harriet Lane Handbook, Mobile Medicine Series, Expert Consult: Online and Print, 19e, Jun-2011
978-0-443-06839-3, Mandell: Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Expert Consult Premium Edition - Enhanced Online Features and Print, 7e, Sep-2009
Infectious Disease
Internal Medicine
Family Medicine
Primary Care
Wilderness Medicine/Emergency Medicine
